Felipe Xavier Buson

Research Interests

I am interested in the development of foundational tools for Synthetic Biology as a way of improving our ability to engineer life. Within this field, I would like to harness the potential of biological computation and genetic circuits to reliably control biological systems in increasingly complex networks. Recently I have also been particularly interested in synthetic biology part metrology, automation, and how the implementations of measurement standards can improve bioengineering.


Education

2024 to present – PhD in Engineering Biology, funded by the Engineering Biology CDT, University of Bristol, UK.

2019 to 2020 – MSc Synthetic Biology and Biotechnology (with Distinction), University of Edinburgh, Edinburgh, Scotland, UK.

2015 to 2018 – Bachelor’s in Biological Sciences, Universidade de São Paulo (USP), São Paulo, SP, Brazil.

2012 to 2014 – Colegio Marista de Brasilia (High School), Brasilia, DF, Brazil.


Work Experience

Sep 2022 – Sep 2024 – Research Assistant at the Open Bioeconomy Lab, supervised by Dr. Jenny Molloy, working in an SBOL-based database of synthetic biology parts and collaborators and developing open-access protocols with the Opentrons OT-2 automation platform.

2019 – Characterization of Serine Integrases for Plant Synthetic Biology, internship work at Dr. Elibio Rech’s laboratory at EMBRAPA (Brazilian Agricultural Research Corporation).


Publications

Annese, D. et al. Semi-automated workflow for high-throughput Agrobacterium-mediated plant transformation. bioRxiv (2024) https://doi.org/10.1101/2024.10.09.617252

Buson, F., Gao, Y. & Wang, B. Genetic parts and enabling tools for biocircuit design. ACS Synthetic Biology (2024) https://doi.org/10.1021/acssynbio.3c00691

Molino, J. V. et al. Chimeric spider silk production in microalgae: a modular bionanomaterial. Research Ideas and Outcomes 2 e9342 (2016) https://doi.org/10.3897/rio.2.e9342


Awards and Presentations

Oct 2020 – MSc Synthetic Biology and Biotechnology programme prize, for obtaining the best grades in the taught and research sections of the programme and being ranked first in my class.

Oct 2018 – Silver medal and ‘Best Measurement’ prize for the Overgraduate category in iGEM 2018, for the implementation of ratiometric measurement standards for genetic circuits and developing accessible methods for fluorescent reporter measurement. - https://2018.igem.org/Team:USP-Brazil

Jan 2018 – VII Southern-Summer School on Mathematical Biology, hosted by the Institute of Theoretical Physics, UNESP - Work modelling ecological dynamics using ODE’s in R and MATLAB and a presentation of my work.

Nov 2017 – Overgraduate Gold medal in the iGEM Giant Jamboree - https://2017.igem.org/Team:USP-Brazil

Oct 2016 – Overgraduate Silver medal in the iGEM Giant Jamboree - https://2016.igem.org/Team:USP_UNIFESP-Brazil


Other skills

Languages – Portuguese (native), English (advanced), German (A2).

Programming - Masters level experience in BASH and Python and bachelor level courses in R. I also have experience with HTML, CSS and JavaScript obtained through iGEM projects and my MSc research project. I feel confident in applying any of these in new projects. I also have experience with C++ and C# from side projects.

Automation – Experience with the Opentrons OT2 platform for molecular biology protocols using Python API and Jupyter Notebooks. Currently working on developing protocols for pathway assembly and characterization at the Open Bioeconomy Lab.


Last updated 15/11/2024